mission & strategy

Innovative targeted therapies for people of all ages

Children with cancer in the U.S. first gain access to cutting-edge investigational treatments an average of 6.5 years later than adults. As a result, only 12 new drugs have been approved to treat cancers seen primarily in children in the last 25 years.

We believe we can do better.

Recent advances in cancer research enable us to identify children and adults who may benefit from the same medicine based on a tumor’s underlying biology. Day One was created to bridge the disparity in treatment access and innovation for children with cancer – and we’re just getting started.


Inspired by the urgent needs of children with cancer, Day One creatively and intentionally develops new medicines for people of all ages with life-threatening diseases.

Our goal is to advance targeted therapies that can help both children and adults. We strategically partner with biopharmaceutical companies, leading clinicians, families, and scientists to identify, acquire, develop and commercialize emerging new treatments for cancer and other life-threatening diseases. We prioritize programs that can be rapidly introduced to support access for both younger and older patients.

Through our mission-driven strategy, we are leading the way in targeted therapies for cancer and life-threatening diseases.

Our name was inspired by “The Day One Talk.” We exist to dramatically change the outlook for families who receive the life-altering news of a challenging diagnosis and the need for a treatment plan. And we won’t stop until we get there.

We are working to redefine what’s possible for people with life-threatening diseases – whatever their age – starting from Day One.

Partner with us to redefine what’s possible.